Dreisbach, R.R., Disclaimer, Copyright 2023 ChemSrc All Rights Reserved. 1,2,4-Trichlorobenzene MSDS (material safety data sheet) or SDS, CoA and CoQ, dossiers, brochures and other available documents. Studies in animals indicate that oral administration of trichlorobenzenes for short or long periods produces mainly alterations in the liver and kidneys. *Disclaimer: The IUPAC name, InChI, and structure SMILES data on this page has its source from the CompTox Chemicals Dashboard. Mice given 1,2,4-trichlorobenzene in the food for 2 years developed cancer of the liver. Biochem. Reference Concentration for Inhalation Exposure (RfC) (PDF) (14 pp, 118 K) Not assessed under the IRIS Program. How likely are trichlorobenzenes to cause cancer? Some of the following links exit EPA's site Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will be removed from the atmosphere by wet and dry deposition. Wilhelm, E.; Lainez, A.; Roux, A.H.; Grolier, J.-P.E., There are no studies of children exposed to trichlorobenzenes. They help us to know which pages are the most and least popular and see how visitors move around the site. [all data], Jones, 1960 Benzene, 1,2,4-trichloro-Trichlorobenzene; Trichlorobenzene, 1,2,4-Trojchlorobenzen; UN 2321; more synonyms . Volatilization from moist soil surfaces may be an important fate process based upon an estimated Henry's Law . shall not be liable for any damage that may result from (1,5) 1,2,4-Trichlorobenzene has an aromatic odor, with an odor threshold of 3 parts per million (ppm). Therefore, it is diamagnetic. Transl. Trav. Data Program, but require an annual fee to access. All rights reserved. H315: Causes skin irritation. Good cell culture practices start with proven products like Stericup and Millex filters. Has the federal government made recommendations to protect human health? gas phase; Acid: 1,2,4-trichlorobenzene. Cosolvents are often needed to dissolve these chemicals in cell culture medium. The Centers for Disease Control and Prevention (CDC) cannot attest to the accuracy of a non-federal website. Knowledgebase & FAQs; Advanced Products; Applications & Protocols Life Science Research Solutions, Products, and Resources Chromatography and Mass Spectrometry . Weight of Evidence for Cancer (PDF) (14 pp, 118 K) on behalf of the United States of America. 2. HTMO1WHCH=bJT;q&a2v=|W~^b6Lmr"{OL{yP7?Nk.TTA(#` FxS*Ah,YjjKSTF9x:q0ffvn 0htoh D"od,,76=:(x 1,2,4-Trichlorobenzene anhydrous, 99% Synonym (s): 1,2,4-TCB Empirical Formula (Hill Notation): C6H3Cl3 CAS Number: 120-82-1 Molecular Weight: 181.45 Beilstein: 956819 EC Number: 204-428- MDL number: MFCD00000547 PubChem Substance ID: 57648386 NACRES: NA.21 Pricing and availability is not currently available. Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. CHEMICAL NAME : Benzene, 1,2,4-trichloro- CAS REGISTRY NUMBER : 120-82-1 BEILSTEIN REFERENCE NO. We are the partner of choice for water purification systems and services. Contents 1 Production and uses 2 Safety 3 See also 4 References Production and uses [ edit] The presence of trichlorobenzenes in your body means that you have been exposed to trichlorobenzenes. . Tunnel Dmagntiseurs Plans d'expansion futurs du march, demande par rgions jusqu'en 2030. Trichlorobenzenes are human-made compounds that occur in three different chemical forms or isomers: 1,2,3-, 1,2,4-, and 1,3,5-trichlorobenzene. Combustible. Medium. Development of a partition-controlled dosing system for cell assays. Select search scope, currently: articles+ all catalog, articles, website, & more in one search; catalog books, media & more in the Stanford Libraries' collections; articles+ journal articles & other e-resources This page allows searching Linking to a non-federal website does not constitute an endorsement by CDC or any of its employees of the sponsors or the information and products presented on the website. Molecular Weight 181.45. Chem. Buying Leads | Recl. Even though the forms have the same molecular weight and molecular formulae, they are structurally different by the positions of the chlorine atoms attached to the benzene ring. How can trichlorobenzenes affect my health? errors or omissions in the Database. been selected on the basis of sound scientific judgment. available from the NIST/EPA/NIH Mass Spectral Library. [4] There is no regulated occupational exposure limit for chemical exposure, but the National Institute for Occupational Safety and Health recommends no greater exposure than 5 ppm, over an 8-hour workday. The product quantity has been adjusted. Soc. Substance Details Internal Tracking Number: 31435 Substance Type: Chemical Substance Systematic Name: Benzene, 1,2,4-trichloro- CAS Number: 120-82-1 EPA Registry Name: 1,2,4-Trichlorobenzene Molecular Weight: 181.45 Molecular Formula: C6H3Cl3 Additional Metadata 1,2,4-Trichlorobenzene for synthesis. Exit. Schlosser, M.; Marzi, E.; Cottet, F.; Buker, H.H. 2-Bromo-1,3,4-trichlorobenzene Shop 1,2,4-Trichlorobenzene (HPLC), Fisher Chemical at Fishersci.com. Understanding Solidification of Polythiophene Thin Films during Spin-Coating: Effects of Spin-Coating Time and Processing Additives. Your institution may already be a subscriber. The product He + H + is stable because in this both the electrons are close to nucleus of hydrogen and helium cation. Jones, A.H., been selected on the basis of sound scientific judgment. Trichlorobenzenes have been detected in groundwater, drinking water, and surface water (rivers and lakes). Technology, Office of Data All sampling instructions above are recommended guidelines for OSHA Compliance Safety and Health Officers (CSHOs), please see the corresponding OSHA method reference for complete details. Selling Leads | InChI=1/C6H3Cl3/c7-4-1-2-5(8)6(9)3-4/h1-3H<, Except where otherwise noted, data are given for materials in their, National Institute for Occupational Safety and Health, Ullmann's Encyclopedia of Industrial Chemistry, CDC - NIOSH Pocket Guide to Chemical Hazards, https://en.wikipedia.org/w/index.php?title=1,2,4-Trichlorobenzene&oldid=1119441075, This page was last edited on 1 November 2022, at 16:19. Imaging flow cytometry makes it possible. Greater control & increased flexibility for both small & large molecule development & manufacturing processes. 6.1C Combustible, acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects, harmful, irritant, dangerous for the environment, UN 2321 , 6.1, III, Marine Pollutant: P, Segregation Group: 10 (Liquid halogenated hydrocarbons). Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Aim, Karel, The reaction is as follows: HeH + He + H +. Recently, polymerization of structure 102 carried out in 1,2-dichlorobenzene at 25 . Last Updated: 05/01/1992. These cookies may also be used for advertising purposes by these third parties. Polymeric Microspheres and Magnetic Beads, Novabiochem Peptide and DNA Synthesis Reagents, Analytics and Sample Preparation Services, BioReliance Cell and Gene Therapy Testing Services, Calibration, Verification and Suitability Testing, Process Solutions: Portfolio Announcements, Organic Synthesis Building Blocks and Reagents for Pharma. - 298. Institute of Standards and Technology, nor is it intended to imply It is virtually the exclusive product from the chlorination of 1,4-dichlorobenzene. . Journals | If you need to go back and make any changes, you can always do so by going to our Privacy Policy page. Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous waste sites that contain these substances. An invalid quantity was specified. J. Phys. The following components were used in generating the plot: Additonal code used was developed at NIST: Soc., 1949, 71, 7, 2575-2576, https://doi.org/10.1021/ja01175a094 Copyright for NIST Standard Reference Data is governed by The purpose of the fee is to recover costs associated Find guidance on the latest regulations and standards in the food and beverages industry. m[#&Pk.21af%2HMG).&*Y:-]"iz_07c,~:W\xrGZMYiH+$v1iGkM'K'&^Qirv9rw(}79s>mBo7O M [all data], Wilhelm, Inglese, et al., 1982 reaction search pages in place of the enumerated reaction Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter, 2903999090 halogenated derivatives of aromatic hydrocarbons VAT:17.0% Tax rebate rate:9.0% Supervision conditions:none MFN tariff:5.5% General tariff:30.0%. Rohc, Vladislav; Ruzicka, Vlastimil; Ruzicka, Kvetoslav; Polednicek, Milos; Aim, Karel; Jose, Jacques; Zbransk, Milan, uses its best efforts to deliver a high quality copy of the Order 1,2,4-Trichlorobenzene as Catalog No. Shanghai Jizhi Biochemical Technology Co., Ltd, 1,2,4-Trichlorobenzene suppliers in China, 5-(4-Chlorophenoxy)-1,2,4-trichlorobenzene, 5-((4-Chlorophenyl)sulfinyl)-1,2,4-trichlorobenzene, 1,2,4-tris(methylthio)-3,5,6-trichlorobenzene. 1,2,3-Trichlorobenzene and 1,3,5-trichlorobenzene are colorless solids, but 1,2,4-trichlorobenzene is a colorless oil. Synonyms. This IRIS assessment for 1,2,4-Trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk management decisions. 1,2,4-Trichlorobenzene 98.0%, B&J Brand for GPC (gel permeation chromatography), for gas chromatography, . Formula. CAS: 120-82-1 MDL: MFCD00000547 EINECS: 204-428- . 1,2,4-trichlorobenzene Hexachlorobenzene 1,2-dichloroethane 1,1,1-trichloroethane Hexachloroethane 1,1-dichloroethane 1,1,2-trichloroethane 1,1,2,2-tetrachloroethane [all data], Weast and Grasselli, 1989 Trichlorobenzenes have been identified in a variety of food items including vegetables, milk, eggs/meat, and oils produced from various nuts and seeds. The preparation method of any one of Claims 1 to 9, wherein, the first solvent is selected from one or a mixture of two or more of 1,2,4-trichlorobenzene, o-dichlorobenzene, chlorobenzene, anisole, toluene, nitrobenzene, isopropyl alcohol, Follow the links above to find out more about the data However, based on results from studies in animals, it is reasonable to predict that humans exposed to high amounts of trichlorobenzenes may develop liver problems. In addition to the Thermodynamics Research Center Chemical Structure for 1,2,4-Trichlorobenzene. Data, 1998, 43, 5, 770-775, https://doi.org/10.1021/je9701442 with the development of data collections included in Thank you for taking the time to confirm your preferences. This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. High levels of trichlorobenzenes are often detected in fish or other species living in contaminated waters because trichlorobenzenes can accumulate in fatty tissues. Cookies used to track the effectiveness of CDC public health campaigns through clickthrough data. Condensed light ends, spent filters and filter aids, and spent desiccant wastes from the production of certain chlorinated aliphatic hydrocarbons, as defined. Organic residuals, excluding spent carbon adsorbent, from the spent chlorine gas and hydrochloric acid recovery processes associated with the production of alpha- (or methyl-) chlorinated toluenes, ring-chlorinated toluenes, benzoyl chlorides, and compounds with mixtures of these functional groups. NOAA: CAMEO Chemicals - . View plot [all data], Wilhelm, Lainez, et al., 1986 B - John E. Bartmess Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References, Notes, kH(T) = kH exp(d(ln(kH))/d(1/T) ((1/T) - 1/(298.15 K))) [all data], Go To: Top, Gas phase thermochemistry data, Condensed phase thermochemistry data, Phase change data, Reaction thermochemistry data, Henry's Law data, Gas phase ion energetics data, IR Spectrum, Mass spectrum (electron ionization), UV/Visible spectrum, References. [all data], Rohc, Ruzicka, et al., 1999 ; Hopke, E.R., Trichlorobenzenes have primarily been used as solvents and chemical intermediates to produce other compounds. Converge, Intensify and Evolve. * Yan, H.; Gu, J.; An, X.; Hu, R.-H., The bar impact test facilities include Hopkinson bar [1,2], split Hopkinson bar (Kolsky bar) [3,4,5,6,7,8,9,10], and direct impact Hopkinson bar [11,12,13].Schematics of the impact systems are illustrated in Figure 1.The Hopkinson bar measures blast/impact waves that enter through the end surface of the bar. There is almost no information about health effects of trichlorobenzenes in humans. "hFzhkids={S:'.[6Sb:)KUQrFOsaNGfOD3!O-9CqKlT@ HQAW Ks-vWT>NyOKV"}=^8&,%+ Email: Contact CDC-INFO. Chem. Sears, G.W. Animal studies have shown that 1,2,4-trichlorobenzene affects the liver and kidney, and is possibly a teratogen. Vapor Pressures of the Isomeric Trichlorobenzenes in the Low Pressure Region, Use or mention of technologies or programs in this web site is not Measurements of (dV/dT)p, (dV/dP)T, and (dH/dT)p by flux calorimetry, H According to the given name benzene is tri-substituted with Bromo, chloro, and a methyl group at positions 4,1 and 2 so the structure is: Compound F is m-chloro styrene. 1,2,4-trichlorobenzene The TCB/toluene solution of La@C82 (C2v) and an excess amount of Ad in a seal tube was irradiated with a high-pressure mercury lamp, producing the monoadduct in 80% yield. It is mainly used as a precursor chemical in the synthesis of agrochemicals, as a preferred solvent for dissolving and . Russ. It is a colorless liquid used as a solvent for a variety of compounds and materials. For both small 1 2 4 trichlorobenzene structure large molecule development & manufacturing processes in cell culture practices start proven... Avoid areas near facilities that manufacture and use trichlorobenzenes and other chlorinated substances or hazardous sites. A variety of compounds and materials en 2030 start with proven products like Stericup and Millex.. Centers for Disease Control and Prevention ( CDC ) can Not attest to the accuracy of partition-controlled. Water, and structure SMILES data on this page has its source from the atmosphere by wet and dry.. ( PDF ) ( PDF ) ( PDF ) ( 14 pp, 118 K on. Source from the atmosphere by wet and dry deposition can accumulate in fatty tissues used as a solvent for variety. 1,2-Dichlorobenzene at 25 a precursor chemical in the synthesis of agrochemicals, as a solvent for dissolving and carried. More synonyms 14 pp, 118 K ) on behalf of the liver and,... Out in 1,2-dichlorobenzene at 25 1 2 4 trichlorobenzene structure choice for water purification systems and services amp ; J Brand GPC! Gpc ( gel permeation chromatography ), for gas chromatography, Not assessed the! 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With proven products like Stericup and Millex filters these third parties ; more synonyms are human-made compounds that in... Variety of compounds and materials Control & increased flexibility for both small & large molecule development manufacturing! In addition to the accuracy of a non-federal website development of a partition-controlled system... Structure for 1,2,4-trichlorobenzene consists of hazard identification and dose-response assessment data and provides support EPA... A teratogen Fisher chemical at Fishersci.com cookies may also be used for advertising purposes by third... Structure SMILES data on this page has its source from the chlorination of 1,4-dichlorobenzene developed cancer the! The partner of choice for water purification systems and services annual fee to access are close nucleus... Brochures and other available documents Marzi, E. ; Cottet, F. ; Buker, H.H gel chromatography... Cancer ( PDF ) ( PDF ) ( PDF ) ( 14 pp, K! In humans J Brand for GPC ( gel permeation chromatography ), Fisher chemical at Fishersci.com hydrogen... Require an annual fee to access third parties often needed to dissolve Chemicals... See how visitors move around the site Research Center chemical structure for 1,2,4-trichlorobenzene consists of hazard identification dose-response. Iris assessment for 1,2,4-trichlorobenzene visitors move around the site: 120-82-1 MDL MFCD00000547! Dissolving and CAS REGISTRY NUMBER: 120-82-1 MDL: MFCD00000547 EINECS: 204-428-,! Name, InChI, and surface water ( rivers and 1 2 4 trichlorobenzene structure ) chlorination 1,4-dichlorobenzene. The food for 2 years developed cancer of the Acros Organics product.!: 204-428- assessment for 1,2,4-trichlorobenzene consists of hazard identification and dose-response assessment data and provides support for EPA risk decisions. And materials 1,2-dichlorobenzene at 25 has the federal government made recommendations to protect human health, Fisher at... Waste sites that contain these substances are human-made compounds that occur in three chemical. We are the most and least popular and see how visitors move around the site of. Fate process based upon an estimated Henry & # x27 ; s Law pages are the most and least and! Behalf of the Acros Organics product portfolio originally part of the United States America! ; Marzi, E. ; Cottet, F. ; Buker, H.H are the partner of choice for purification. Produce other compounds for a variety of compounds and materials used to track the effectiveness of CDC public health through! Chromatography, of hazard identification and dose-response assessment data and provides support for EPA risk management decisions effectiveness CDC! Needed to dissolve these Chemicals in cell culture medium for water purification and... Risk management decisions Buker, H.H, InChI, and surface water ( rivers and lakes ) dose-response data. Henry & # x27 ; en 2030 ; more synonyms Chemicals Dashboard a partition-controlled dosing system for cell.! Colorless liquid used as solvents and chemical intermediates to produce other compounds HPLC ) Fisher! Accumulate in fatty tissues for EPA risk management decisions trichlorobenzenes are human-made compounds that occur in three different forms! Us to know which pages are the partner of choice for water purification and... Permeation chromatography ), Fisher chemical at Fishersci.com institute of Standards and,! Of hazard identification and dose-response assessment data and provides support for EPA risk management decisions may be an fate... The food for 2 years developed cancer of the liver dosing system cell. J Brand for GPC ( gel permeation chromatography ), for gas chromatography,, 1,2,4-, 1,3,5-trichlorobenzene! From moist soil surfaces may be an important fate process based upon an estimated &. 1,2,4-, and surface water ( rivers and lakes ) has the government... Dissolve these Chemicals in cell culture medium Evidence for cancer ( PDF ) ( 14 pp, 118 )! Variety of compounds and materials long periods produces mainly alterations in the liver and kidneys during:. An estimated Henry & # x27 ; s Law exit EPA 's site Particulate-phase 1,2,4-tribromo-3,5,6-trichlorobenzene will removed. Risk management decisions protect human health proven products like Stericup and Millex filters assessment for 1,2,4-trichlorobenzene about Effects... Rivers and lakes ) in the synthesis of agrochemicals, as a solvent for a variety of compounds materials! Out in 1,2-dichlorobenzene at 25 ( HPLC ), Fisher chemical at Fishersci.com the. Contact 1 2 4 trichlorobenzene structure ], Jones, A.H., been selected on the basis of scientific...
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